It is a common misconception that margarine is a superior choice to butter because margarine is made from vegetable oil and vegetable oil is lower in cholesterol than animal fat such as butter. This is only half the story. Natural vegetable oil may be lower in cholesterol than butter but margarine is toxic to the body and can cause high cholesterol.
Margarine is a hydrogenated vegetable oil. This means that vegetable oil, which is normally liquid at room temperature, has undergone an artificial process to make it solid at room temperature. Going from liquid to solid may seem like an innocuous change. However, chemists and researchers are increasingly understanding the chemistry of this change and how it creates a false fat that (1) cannot be absorbed by the body and (2) causes internal damage.